Single Cell and Spatial Omics
Abiosciences Genomics Laboratory offers end-to-end single-cell and spatial solutions from sample processing to library construction to sequencing.
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With our extensive experience in single-cell and spatial experiments, we profile complex tissues utilizing state-of-the-art technologies. We have three core capabilities: integrated multi-omics on fresh/cryopreserved specimens, integrated tissue genomics on frozen samples, and spatial transcriptome from fixed tissues.
Our offerings include the following:
Single-cell Multi-omics with RNA and protein sequencing (CITE-seq)
Integrated tissue genomics from frozen tissues
Spatial transcriptome from fixed tissues
Combining BioLegend Total-seq antibody panels and 10x Genomics single-cell gene expression sequencing, CITE-seq approaches help to annotate cell subtypes and identify rare cell population. The protein expression data can be used similarly to flow cytometry method to gate sub-populations in order to understand their gene expression profiles.
Tim Stuart, et al, Cell, 2019
